Fish scales and teeth share an embryonic origin

Fish scales and teeth share an embryonic origin

Latest research supports the theory that teeth in the animal kingdom evolved from the jagged scales of ancient fish, the remnants of which can be seen today embedded in the skin of sharks and skate, according to researchers at the University of CambridgeThis ancient dermal skeleton has undergone considerable reductions and modifications through time.

Recent studies on species such as zebrafish showed scales and teeth developing from distinctly different clusters of cells in fish embryos, pouring cold water on ‘teeth from scales’ theories. However, while most fish in the sea have bones, one ancient lineage – sharks, skates and rays – possess skeletons made entirely of cartilage.

These cartilaginous fish retain some primitive characteristics that have been lost in their bony counterparts, including small spiky scales embedded in their skin called ‘dermal denticles’ that bear a striking resemblance to jagged teeth.  Now, researchers at the University of Cambridge have used fluorescent markers to track cell development in the embryo of a cartilaginous fish – a little skate in this case – and found that these thorny scales are in fact created from the same type of cells as teeth: neural crest cells.

The findings, published in the journal PNAS, support the theory that, in the depths of early evolution, these ‘denticle’ scales were carried into the emerging mouths of jawed vertebrates to form teeth. Jawed vertebrates now make up 99% of all living vertebrates, from fish to mammals.

“The scales of most fish that live today are very different from the ancient scales of early vertebrates,” says study author Dr Andrew Gillis from Cambridge’s Department of Zoology and the Marine Biological Laboratory in Woods Hole. “Primitive scales were much more tooth-like in structure, but have been retained in only a few living lineages, including that of cartilaginous fishes such as skates and sharks.

“Stroke a shark and you’ll find it feels rougher than other fish, as shark skin is covered entirely in dermal denticles. There’s evidence that shark skin was actually used as sandpaper as early as the Bronze Age,” says Gillis, “By labelling the different types of cells in the embryos of skate, we were able to trace their fates. We show that, unlike most fish, the denticle scales of sharks and skate develop from neural crest cells, just like teeth.

“Neural crest cells are central to the process of tooth development in mammals. Our findings suggest a deep evolutionary relationship between these primitive fish scales and the teeth of vertebrates. Early jawless vertebrates were filter feeders – sucking in small prey items from the water. It was the advent of both jaws and teeth that allowed vertebrates to begin processing larger and more complex prey.”

Source: http://www.cam.ac.uk/research/news/ancient-fish-scales-and-vertebrate-teeth-share-an-embryonic-origin

 

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