29 March 2023

• Nocebo response in third molar analgesic trials

  This review estimating the nocebo response in dentistry from trials of analgesic treatment following third molar surgery included data from 50 RCTs. Adverse events (AEs) were roughly the same in placebo and active arms suggesting AEs may be attributed to the nocebo phenomenon.

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• Acute pain management following dental extraction

  This review and network meta-analysis (NMA) of pharmacological treatments for the management of pain subsequent to simple and surgical tooth extraction included 85 RCTs. There was moderate- and high-certainty evidence that for surgical dental extractions that ibuprofen 200 to 400 mg plus acetaminophen 500 to 1,000 mg was the most effective for pain relief.

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• Peri-implant mucositis – patient performed adjunctive measures

  This review of patient-performed or administered measures used adjunctively to submarginal instrumentation for the management of peri-implant mucositis included 14 studies. The findings indicated that adjunctive measures reduced probing depth, bleeding on probing and plaque level reductions at 3 months and were in favour of adjunctive measures, which were plaque.

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